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Role of T Cell Receptor Affinity in the Efficacy and Specificity of Adoptive T Cell Therapies
Over the last several years, there has been considerable progress in the treatment of cancer using gene modified adoptive T cell therapies. Two approaches have been used, one involving the introduction of a conventional αβ T cell receptor (TCR) against a pepMHC cancer antigen, and the second involvi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748443/ https://www.ncbi.nlm.nih.gov/pubmed/23970885 http://dx.doi.org/10.3389/fimmu.2013.00244 |