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Role of T Cell Receptor Affinity in the Efficacy and Specificity of Adoptive T Cell Therapies

Over the last several years, there has been considerable progress in the treatment of cancer using gene modified adoptive T cell therapies. Two approaches have been used, one involving the introduction of a conventional αβ T cell receptor (TCR) against a pepMHC cancer antigen, and the second involvi...

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Detalles Bibliográficos
Autores principales:	Stone, Jennifer D., Kranz, David M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748443/ https://www.ncbi.nlm.nih.gov/pubmed/23970885 http://dx.doi.org/10.3389/fimmu.2013.00244

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