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Single-Molecule Measurements of Transient Biomolecular Complexes through Microfluidic Dilution

[Image: see text] Single-molecule confocal microscopy experiments require concentrations which are low enough to guarantee that, on average, less than one single molecule resides in the probe volume at any given time. Such concentrations are, however, significantly lower than the dissociation consta...

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Detalles Bibliográficos
Autores principales: Horrocks, Mathew H., Rajah, Luke, Jönsson, Peter, Kjaergaard, Magnus, Vendruscolo, Michele, Knowles, Tuomas P. J., Klenerman, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748451/
https://www.ncbi.nlm.nih.gov/pubmed/23782428
http://dx.doi.org/10.1021/ac4010875