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Macromolecular juggling by ubiquitylation enzymes

The posttranslational modification of target proteins with ubiquitin and ubiquitin-like proteins is accomplished by the sequential action of E1, E2, and E3 enzymes. Members of the E1 and E3 enzyme families can undergo particularly large conformational changes during their catalytic cycles, involving...

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Detalles Bibliográficos
Autores principales: Lorenz, Sonja, Cantor, Aaron J, Rape, Michael, Kuriyan, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748819/
https://www.ncbi.nlm.nih.gov/pubmed/23800009
http://dx.doi.org/10.1186/1741-7007-11-65