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A Heterologous Prime/Boost Vaccination Strategy Enhances the Immunogenicity of Therapeutic Vaccines for Hepatitis C Virus

Background. We explored the concept of heterologous prime/boost vaccination using 2 therapeutic vaccines currently in clinical development aimed at treating chronically infected hepatitis C virus (HCV) patients: prime with a DNA-based vaccine expressing HCV genotype 1a NS3/4A proteins (ChronVac-C) a...

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Detalles Bibliográficos
Autores principales: Fournillier, Anne, Frelin, Lars, Jacquier, Emilie, Ahlén, Gustaf, Brass, Anette, Gerossier, Estelle, Holmström, Fredrik, Broderick, Kate E., Sardesai, Niranjan Y., Bonnefoy, Jean-Yves, Inchauspé, Geneviève, Sällberg, Matti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749006/
https://www.ncbi.nlm.nih.gov/pubmed/23776192
http://dx.doi.org/10.1093/infdis/jit267