Synthesis and evaluation of mutual azo prodrug of 5-aminosalicylic acid linked to 2-phenylbenzoxazole-2-yl-5-acetic acid in ulcerative colitis

In this study, the syntheses of 4-aminophenylbenzoxazol-2-yl-5-acetic acid, (an analogue of a known nonsteroidal anti-inflammatory drug [NSAID]) and 5-[4-(benzoxazol-2-yl-5-acetic acid)phenylazo]-2-hydroxybenzoic acid (a novel mutual azo prodrug of 5-aminosalicylic acid [5-ASA]) are reported. The st...

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Detalles Bibliográficos
Autores principales: Jilani, Jamal A, Shomaf, Maha, Alzoubi, Karem H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749060/
https://www.ncbi.nlm.nih.gov/pubmed/23983456
http://dx.doi.org/10.2147/DDDT.S48636

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749060/
https://www.ncbi.nlm.nih.gov/pubmed/23983456
http://dx.doi.org/10.2147/DDDT.S48636

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