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Cardiac Fibroblast-Dependent Extracellular Matrix Accumulation Is Associated with Diastolic Stiffness in Type 2 Diabetes

Cardiovascular complications are a leading cause of death in patients with type 2 diabetes mellitus (T2DM). Diastolic dysfunction is one of the earliest manifestations of diabetes-induced changes in left ventricular (LV) function, and results from a reduced rate of relaxation and increased stiffness...

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Detalles Bibliográficos
Autores principales: Hutchinson, Kirk R., Lord, C. Kevin, West, T. Aaron, Stewart, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749105/
https://www.ncbi.nlm.nih.gov/pubmed/23991045
http://dx.doi.org/10.1371/journal.pone.0072080