Cargando…
Cardiac Fibroblast-Dependent Extracellular Matrix Accumulation Is Associated with Diastolic Stiffness in Type 2 Diabetes
Cardiovascular complications are a leading cause of death in patients with type 2 diabetes mellitus (T2DM). Diastolic dysfunction is one of the earliest manifestations of diabetes-induced changes in left ventricular (LV) function, and results from a reduced rate of relaxation and increased stiffness...
Autores principales: | Hutchinson, Kirk R., Lord, C. Kevin, West, T. Aaron, Stewart, James A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749105/ https://www.ncbi.nlm.nih.gov/pubmed/23991045 http://dx.doi.org/10.1371/journal.pone.0072080 |
Ejemplares similares
-
Extracellular Matrix Stiffness and Composition Regulate the Myofibroblast Differentiation of Vaginal Fibroblasts
por: Ruiz-Zapata, Alejandra M., et al.
Publicado: (2020) -
Sitagliptin Inhibits Extracellular Matrix Accumulation and Proliferation in Lung Fibroblasts
por: Liu, Xiuwu, et al.
Publicado: (2020) -
Fibroblastic Transformation of Corneal Keratocytes by Rac Inhibition is Modulated by Extracellular Matrix Structure and Stiffness
por: Petroll, W. Matthew, et al.
Publicado: (2015) -
Cardiac Fibroblasts and the Extracellular Matrix in Regenerative and Nonregenerative Hearts
por: Hortells, Luis, et al.
Publicado: (2019) -
β3 Integrin in Cardiac Fibroblast Is Critical for Extracellular Matrix Accumulation during Pressure Overload Hypertrophy in Mouse
por: Balasubramanian, Sundaravadivel, et al.
Publicado: (2012)