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Circulating Tumor Cells: Application as a Biomarker for Molecular Characterization and Predictor of Survival in an All-Comer Solid Tumor Phase I Clinical Study

PURPOSE: Clinical development of cancer drugs has a low success rate. Prognostic and predictive biomarkers using minimally invasive approaches hold promise for increasing the probability of success by enabling disease characterization, patient selection and early detection of drug treatment effect....

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Detalles Bibliográficos
Autores principales: Bao, Haifeng, Burke, Patricia A., Huang, Jiaqi, Chen, Xiaoru, Brohawn, Philip Z., Yao, Yihong, Lechleider, Robert J., Sikorski, Robert S., Buzoianu, Manuela, Zhang, Jianliang, Shi, Xiaoqing, Richman, Laura K., LaVallee, Theresa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749129/
https://www.ncbi.nlm.nih.gov/pubmed/23990866
http://dx.doi.org/10.1371/journal.pone.0058557