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Hypomethylation of Alu Elements in Post-Menopausal Women with Osteoporosis
A decrease in genomic methylation commonly occurs in aging cells; however, whether this epigenetic modification leads to age-related phenotypes has not been evaluated. Alu elements are the major interspersed repetitive DNA elements in humans that lose DNA methylation in aging individuals. Alu demeth...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749148/ https://www.ncbi.nlm.nih.gov/pubmed/23990903 http://dx.doi.org/10.1371/journal.pone.0070386 |