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Folic Acid Conjugated δ-Valerolactone-Poly(ethylene glycol) Based Triblock Copolymer as a Promising Carrier for Targeted Doxorubicin Delivery

The aim of this study is to test the hypothesis that the newly synthesized poly(δ-valerolactone)/poly(ethylene glycol)/poly(δ-valerolactone) (VEV) copolymer grafted with folic acid would impart targetability and further enhance the anti-tumor efficacy of doxorubicin (DOX). Here, folic acid conjugate...

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Detalles Bibliográficos
Autores principales: Nair K, Lekha, Jagadeeshan, Sankar, Nair S, Asha, Kumar, G. S. Vinod
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749165/
https://www.ncbi.nlm.nih.gov/pubmed/23990912
http://dx.doi.org/10.1371/journal.pone.0070697