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DNA Methylation Profiling of the Fibrinogen Gene Landscape in Human Cells and during Mouse and Zebrafish Development

The fibrinogen genes FGA, FGB and FGG show coordinated expression in hepatocytes. Understanding the underlying transcriptional regulation may elucidate how their tissue-specific expression is maintained and explain the high variability in fibrinogen blood levels. DNA methylation of CpG-poor gene pro...

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Detalles Bibliográficos
Autores principales: Vorjohann, Silja, Pitetti, Jean-Luc, Nef, Serge, Gonelle-Gispert, Carmen, Buhler, Leo, Fish, Richard J., Neerman-Arbez, Marguerite
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749180/
https://www.ncbi.nlm.nih.gov/pubmed/23991173
http://dx.doi.org/10.1371/journal.pone.0073089