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HDL Induces the Expression of the M2 Macrophage Markers Arginase 1 and Fizz-1 in a STAT6-Dependent Process

Our lab has previously shown in a mouse model that normalization of a low HDL level achieves atherosclerotic plaque regression. This included the shift from a pro (“M1”) to an anti-inflammatory (“M2”) phenotypic state of plaque macrophages. Whether HDL can directly cause this phenotypic change and,...

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Detalles Bibliográficos
Autores principales: Sanson, Marie, Distel, Emilie, Fisher, Edward A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749183/
https://www.ncbi.nlm.nih.gov/pubmed/23991225
http://dx.doi.org/10.1371/journal.pone.0074676