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Genome-Wide Exploration of miRNA Function in Mammalian Muscle Cell Differentiation

MiRNAs impact on the control of cell fate by regulating gene expression at the post-transcriptional level. Here, using mammalian muscle differentiation as a model and a phenotypic loss-of-function screen, we explored the function of miRNAs at the genome-wide level. We found that the depletion of a h...

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Detalles Bibliográficos
Autores principales: Polesskaya, Anna, Degerny, Cindy, Pinna, Guillaume, Maury, Yves, Kratassiouk, Gueorgui, Mouly, Vincent, Morozova, Nadya, Kropp, Jeremie, Frandsen, Niels, Harel-Bellan, Annick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749189/
https://www.ncbi.nlm.nih.gov/pubmed/23991007
http://dx.doi.org/10.1371/journal.pone.0071927