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Contraction and AICAR Stimulate IL-6 Vesicle Depletion From Skeletal Muscle Fibers In Vivo

Recent studies suggest that interleukin 6 (IL-6) is released from contracting skeletal muscles; however, the cellular origin, secretion kinetics, and signaling mechanisms regulating IL-6 secretion are unknown. To address these questions, we developed imaging methodology to study IL-6 in fixed mouse...

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Detalles Bibliográficos
Autores principales: Lauritzen, Hans P.M.M., Brandauer, Josef, Schjerling, Peter, Koh, Ho-Jin, Treebak, Jonas T., Hirshman, Michael F., Galbo, Henrik, Goodyear, Laurie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749330/
https://www.ncbi.nlm.nih.gov/pubmed/23761105
http://dx.doi.org/10.2337/db12-1261