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Plasminogen Activator Inhibitor-1 Is Involved in Streptozotocin-Induced Bone Loss in Female Mice

In diabetic patients, the risk of fracture is high because of impaired bone formation. However, the details of the mechanisms in the development of diabetic osteoporosis remain unclear. In the current study, we investigated the role of plasminogen activator inhibitor (PAI)-1 in the pathogenesis of t...

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Detalles Bibliográficos
Autores principales: Tamura, Yukinori, Kawao, Naoyuki, Okada, Kiyotaka, Yano, Masato, Okumoto, Katsumi, Matsuo, Osamu, Kaji, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749344/
https://www.ncbi.nlm.nih.gov/pubmed/23715621
http://dx.doi.org/10.2337/db12-1552