Relaxin Treatment Reverses Insulin Resistance in Mice Fed a High-Fat Diet

The endogenous hormone relaxin increases vascular reactivity and angiogenesis. We demonstrate that acute relaxin infusion in lean C57BL/6J mice enhances skeletal muscle perfusion and augments muscle glucose uptake during a hyperinsulinemic-euglycemic clamp. However, an acute effect was absent in mic...

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Detalles Bibliográficos
Autores principales: Bonner, Jeffrey S., Lantier, Louise, Hocking, Kyle M., Kang, Li, Owolabi, Mark, James, Freyja D., Bracy, Deanna P., Brophy, Colleen M., Wasserman, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749347/
https://www.ncbi.nlm.nih.gov/pubmed/23801576
http://dx.doi.org/10.2337/db13-0033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749347/
https://www.ncbi.nlm.nih.gov/pubmed/23801576
http://dx.doi.org/10.2337/db13-0033

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