Transient B-Cell Depletion Combined With Apoptotic Donor Splenocytes Induces Xeno-Specific T- and B-Cell Tolerance to Islet Xenografts

Peritransplant infusion of apoptotic donor splenocytes cross-linked with ethylene carbodiimide (ECDI-SPs) has been demonstrated to effectively induce allogeneic donor-specific tolerance. The objective of the current study is to determine the effectiveness and additional requirements for tolerance in...

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Detalles Bibliográficos
Autores principales: Wang, Shusen, Tasch, James, Kheradmand, Taba, Ulaszek, Jodie, Ely, Sora, Zhang, Xiaomin, Hering, Bernhard J., Miller, Stephen D., Luo, Xunrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749362/
https://www.ncbi.nlm.nih.gov/pubmed/23852699
http://dx.doi.org/10.2337/db12-1678

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749362/
https://www.ncbi.nlm.nih.gov/pubmed/23852699
http://dx.doi.org/10.2337/db12-1678

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