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Transient B-Cell Depletion Combined With Apoptotic Donor Splenocytes Induces Xeno-Specific T- and B-Cell Tolerance to Islet Xenografts

Peritransplant infusion of apoptotic donor splenocytes cross-linked with ethylene carbodiimide (ECDI-SPs) has been demonstrated to effectively induce allogeneic donor-specific tolerance. The objective of the current study is to determine the effectiveness and additional requirements for tolerance in...

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Detalles Bibliográficos
Autores principales:	Wang, Shusen, Tasch, James, Kheradmand, Taba, Ulaszek, Jodie, Ely, Sora, Zhang, Xiaomin, Hering, Bernhard J., Miller, Stephen D., Luo, Xunrong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2013
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749362/ https://www.ncbi.nlm.nih.gov/pubmed/23852699 http://dx.doi.org/10.2337/db12-1678

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