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MERS-coronavirus replication induces severe in vitro cytopathology and is strongly inhibited by cyclosporin A or interferon-α treatment

Coronavirus (CoV) infections are commonly associated with respiratory and enteric disease in humans and animals. The 2003 outbreak of severe acute respiratory syndrome (SARS) highlighted the potentially lethal consequences of CoV-induced disease in humans. In 2012, a novel CoV (Middle East Respirato...

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Detalles Bibliográficos
Autores principales: de Wilde, Adriaan H., Raj, V. Stalin, Oudshoorn, Diede, Bestebroer, Theo M., van Nieuwkoop, Stefan, Limpens, Ronald W. A. L., Posthuma, Clara C., van der Meer, Yvonne, Bárcena, Montserrat, Haagmans, Bart L., Snijder, Eric J., van den Hoogen, Bernadette G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for General Microbiology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749523/
https://www.ncbi.nlm.nih.gov/pubmed/23620378
http://dx.doi.org/10.1099/vir.0.052910-0