Cargando…
MERS-coronavirus replication induces severe in vitro cytopathology and is strongly inhibited by cyclosporin A or interferon-α treatment
Coronavirus (CoV) infections are commonly associated with respiratory and enteric disease in humans and animals. The 2003 outbreak of severe acute respiratory syndrome (SARS) highlighted the potentially lethal consequences of CoV-induced disease in humans. In 2012, a novel CoV (Middle East Respirato...
Autores principales: | de Wilde, Adriaan H., Raj, V. Stalin, Oudshoorn, Diede, Bestebroer, Theo M., van Nieuwkoop, Stefan, Limpens, Ronald W. A. L., Posthuma, Clara C., van der Meer, Yvonne, Bárcena, Montserrat, Haagmans, Bart L., Snijder, Eric J., van den Hoogen, Bernadette G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for General Microbiology
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749523/ https://www.ncbi.nlm.nih.gov/pubmed/23620378 http://dx.doi.org/10.1099/vir.0.052910-0 |
Ejemplares similares
-
Antiviral Innate Immune Response Interferes with the Formation of Replication-Associated Membrane Structures Induced by a Positive-Strand RNA Virus
por: Oudshoorn, Diede, et al.
Publicado: (2016) -
Expression and Cleavage of Middle East Respiratory Syndrome Coronavirus nsp3-4 Polyprotein Induce the Formation of Double-Membrane Vesicles That Mimic Those Associated with Coronaviral RNA Replication
por: Oudshoorn, Diede, et al.
Publicado: (2017) -
Biogenesis and architecture of arterivirus replication organelles
por: van der Hoeven, Barbara, et al.
Publicado: (2016) -
SARS-coronavirus-2 replication in Vero E6 cells: replication kinetics, rapid adaptation and cytopathology
por: Ogando, Natacha S., et al.
Publicado: (2020) -
Excessive production and extreme editing of human metapneumovirus defective interfering RNA is associated with type I IFN induction
por: van den Hoogen, Bernadette G., et al.
Publicado: (2014)