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Evolutionary game theory of growth factor production: implications for tumour heterogeneity and resistance to therapies
BACKGROUND: Tumour heterogeneity is documented for many characters, including the production of growth factors, one of the hallmarks of cancer. What maintains heterogeneity remains an open question that has implications for diagnosis and treatment, as drugs that target growth factors are susceptible...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749558/ https://www.ncbi.nlm.nih.gov/pubmed/23922110 http://dx.doi.org/10.1038/bjc.2013.336 |