DUSP6 regulates drug sensitivity by modulating DNA damage response

BACKGROUND: Dual specificity phosphatase 6 (DUSP6) is a member of a family of mitogen-activated protein kinase phosphatases that dephosphorylates and inhibits activated ERK1/2. Dual specificity phosphatase 6 is dynamically regulated in developmental and pathological conditions such as cancer. METHOD...

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Detalles Bibliográficos
Autores principales: Bagnyukova, T V, Restifo, D, Beeharry, N, Gabitova, L, Li, T, Serebriiskii, I G, Golemis, E A, Astsaturov, I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749559/
https://www.ncbi.nlm.nih.gov/pubmed/23839489
http://dx.doi.org/10.1038/bjc.2013.353

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749559/
https://www.ncbi.nlm.nih.gov/pubmed/23839489
http://dx.doi.org/10.1038/bjc.2013.353

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