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DUSP6 regulates drug sensitivity by modulating DNA damage response
BACKGROUND: Dual specificity phosphatase 6 (DUSP6) is a member of a family of mitogen-activated protein kinase phosphatases that dephosphorylates and inhibits activated ERK1/2. Dual specificity phosphatase 6 is dynamically regulated in developmental and pathological conditions such as cancer. METHOD...
Autores principales: | Bagnyukova, T V, Restifo, D, Beeharry, N, Gabitova, L, Li, T, Serebriiskii, I G, Golemis, E A, Astsaturov, I |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749559/ https://www.ncbi.nlm.nih.gov/pubmed/23839489 http://dx.doi.org/10.1038/bjc.2013.353 |
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