Targeting tumour energy metabolism potentiates the cytotoxicity of 5-aminolevulinic acid photodynamic therapy

BACKGROUND: Cancerous cells usually exhibit increased aerobic glycolysis, compared with normal tissue (the Warburg effect), making this pathway an attractive therapeutic target. METHODS: Cell viability, cell number, clonogenic assay, reactive oxygen (ROS), ATP, and apoptosis were assayed in MCF-7 tu...

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Detalles Bibliográficos
Autores principales: Golding, J P, Wardhaugh, T, Patrick, L, Turner, M, Phillips, J B, Bruce, J I, Kimani, S G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749566/
https://www.ncbi.nlm.nih.gov/pubmed/23860536
http://dx.doi.org/10.1038/bjc.2013.391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749566/
https://www.ncbi.nlm.nih.gov/pubmed/23860536
http://dx.doi.org/10.1038/bjc.2013.391

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