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Peroxiredoxin-3 is overexpressed in prostate cancer and promotes cancer cell survival by protecting cells from oxidative stress

OBJECTIVE: We have previously identified peroxiredoxin-3 (PRDX-3) as a cell-surface protein that is androgen regulated in the LNCaP prostate cancer (PCa) cell line. PRDX-3 is a member of the peroxiredoxin family that are responsible for neutralising reactive oxygen species. EXPERIMENTAL DESIGN: PRDX...

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Detalles Bibliográficos
Autores principales: Whitaker, H C, Patel, D, Howat, W J, Warren, A Y, Kay, J D, Sangan, T, Marioni, J C, Mitchell, J, Aldridge, S, Luxton, H J, Massie, C, Lynch, A G, Neal, D E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749568/
https://www.ncbi.nlm.nih.gov/pubmed/23880827
http://dx.doi.org/10.1038/bjc.2013.396