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Proteolytic processing of QSOX1A ensures efficient secretion of a potent disulfide catalyst

QSOX1 (quiescin sulfhydryl oxidase 1) efficiently catalyses the insertion of disulfide bonds into a wide range of proteins. The enzyme is mechanistically well characterized, but its subcellular location and the identity of its protein substrates remain ill-defined. The function of QSOX1 is likely to...

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Detalles Bibliográficos
Autores principales: Rudolf, Jana, Pringle, Marie A., Bulleid, Neil J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749868/
https://www.ncbi.nlm.nih.gov/pubmed/23713614
http://dx.doi.org/10.1042/BJ20130360