Genic Intolerance to Functional Variation and the Interpretation of Personal Genomes

A central challenge in interpreting personal genomes is determining which mutations most likely influence disease. Although progress has been made in scoring the functional impact of individual mutations, the characteristics of the genes in which those mutations are found remain largely unexplored....

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Detalles Bibliográficos
Autores principales: Petrovski, Slavé, Wang, Quanli, Heinzen, Erin L., Allen, Andrew S., Goldstein, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749936/
https://www.ncbi.nlm.nih.gov/pubmed/23990802
http://dx.doi.org/10.1371/journal.pgen.1003709

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749936/
https://www.ncbi.nlm.nih.gov/pubmed/23990802
http://dx.doi.org/10.1371/journal.pgen.1003709

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