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PI3K p110γ Deletion Attenuates Murine Atherosclerosis by Reducing Macrophage Proliferation but Not Polarization or Apoptosis in Lesions

Atherosclerosis is an inflammatory disease regulated by infiltrating monocytes and T cells, among other cell types. Macrophage recruitment to atherosclerotic lesions is controlled by monocyte infiltration into plaques. Once in the lesion, macrophage proliferation in situ, apoptosis, and differentiat...

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Detalles Bibliográficos
Autores principales: Zotes, Teresa M., Arias, Cristina F., Fuster, José J., Spada, Roberto, Pérez-Yagüe, Sonia, Hirsch, Emilio, Wymann, Matthias, Carrera, Ana C., Andrés, Vicente, Barber, Domingo F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750002/
https://www.ncbi.nlm.nih.gov/pubmed/23991137
http://dx.doi.org/10.1371/journal.pone.0072674