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Candidate Gene Analysis of Tooth Agenesis Identifies Novel Mutations in Six Genes and Suggests Significant Role for WNT and EDA Signaling and Allele Combinations

Failure to develop complete dentition, tooth agenesis, is a common developmental anomaly manifested most often as isolated but also as associated with many developmental syndromes. It typically affects third molars or one or few other permanent teeth but severe agenesis is also relatively prevalent....

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Detalles Bibliográficos
Autores principales: Arte, Sirpa, Parmanen, Satu, Pirinen, Sinikka, Alaluusua, Satu, Nieminen, Pekka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750013/
https://www.ncbi.nlm.nih.gov/pubmed/23991204
http://dx.doi.org/10.1371/journal.pone.0073705