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Candidate Gene Analysis of Tooth Agenesis Identifies Novel Mutations in Six Genes and Suggests Significant Role for WNT and EDA Signaling and Allele Combinations
Failure to develop complete dentition, tooth agenesis, is a common developmental anomaly manifested most often as isolated but also as associated with many developmental syndromes. It typically affects third molars or one or few other permanent teeth but severe agenesis is also relatively prevalent....
Autores principales: | Arte, Sirpa, Parmanen, Satu, Pirinen, Sinikka, Alaluusua, Satu, Nieminen, Pekka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750013/ https://www.ncbi.nlm.nih.gov/pubmed/23991204 http://dx.doi.org/10.1371/journal.pone.0073705 |
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