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Gemcitabine Eliminates Double Minute Chromosomes from Human Ovarian Cancer Cells
Double minute chromosomes are cytogenetic manifestations of gene amplification frequently seen in cancer cells. Genes amplified on double minute chromosomes include oncogenes and multi-drug resistant genes. These genes encode proteins which contribute to cancer formation, cancer progression, and dev...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750019/ https://www.ncbi.nlm.nih.gov/pubmed/23991020 http://dx.doi.org/10.1371/journal.pone.0071988 |