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Multiple Host Kinases Contribute to Akt Activation during Salmonella Infection

SopB is a type 3 secreted effector with phosphatase activity that Salmonella employs to manipulate host cellular processes, allowing the bacteria to establish their intracellular niche. One important function of SopB is activation of the pro-survival kinase Akt/protein kinase B in the infected host...

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Detalles Bibliográficos
Autores principales: Roppenser, Bernhard, Kwon, Hyunwoo, Canadien, Veronica, Xu, Risheng, Devreotes, Peter N., Grinstein, Sergio, Brumell, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750030/
https://www.ncbi.nlm.nih.gov/pubmed/23990921
http://dx.doi.org/10.1371/journal.pone.0071015