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Concentration Addition, Independent Action and Generalized Concentration Addition Models for Mixture Effect Prediction of Sex Hormone Synthesis In Vitro

Humans are concomitantly exposed to numerous chemicals. An infinite number of combinations and doses thereof can be imagined. For toxicological risk assessment the mathematical prediction of mixture effects, using knowledge on single chemicals, is therefore desirable. We investigated pros and cons o...

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Detalles Bibliográficos
Autores principales: Hadrup, Niels, Taxvig, Camilla, Pedersen, Mikael, Nellemann, Christine, Hass, Ulla, Vinggaard, Anne Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750043/
https://www.ncbi.nlm.nih.gov/pubmed/23990906
http://dx.doi.org/10.1371/journal.pone.0070490