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Human RNase H1 Is Associated with Protein P32 and Is Involved in Mitochondrial Pre-rRNA Processing

Mammalian RNase H1 has been implicated in mitochondrial DNA replication and RNA processing and is required for embryonic development. We identified the mitochondrial protein P32 that binds specifically to human RNase H1, but not human RNase H2. P32 binds human RNase H1 via the hybrid-binding domain...

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Detalles Bibliográficos
Autores principales: Wu, Hongjiang, Sun, Hong, Liang, Xuehai, Lima, Walt F., Crooke, Stanley T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750045/
https://www.ncbi.nlm.nih.gov/pubmed/23990920
http://dx.doi.org/10.1371/journal.pone.0071006