REACTIN: Regulatory activity inference of transcription factors underlying human diseases with application to breast cancer

BACKGROUND: Genetic alterations of transcription factors (TFs) have been implicated in the tumorigenesis of cancers. In many cancers, alteration of TFs results in aberrant activity of them without changing their gene expression level. Gene expression data from microarray or RNA-seq experiments can c...

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Detalles Bibliográficos
Autores principales: Zhu, Mingzhu, Liu, Chun-Chi, Cheng, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750236/
https://www.ncbi.nlm.nih.gov/pubmed/23885756
http://dx.doi.org/10.1186/1471-2164-14-504

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750236/
https://www.ncbi.nlm.nih.gov/pubmed/23885756
http://dx.doi.org/10.1186/1471-2164-14-504

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