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REACTIN: Regulatory activity inference of transcription factors underlying human diseases with application to breast cancer
BACKGROUND: Genetic alterations of transcription factors (TFs) have been implicated in the tumorigenesis of cancers. In many cancers, alteration of TFs results in aberrant activity of them without changing their gene expression level. Gene expression data from microarray or RNA-seq experiments can c...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750236/ https://www.ncbi.nlm.nih.gov/pubmed/23885756 http://dx.doi.org/10.1186/1471-2164-14-504 |