Evidence for inflammation-mediated memory dysfunction in gastropods: putative PLA(2) and COX inhibitors abolish long-term memory failure induced by systemic immune challenges

BACKGROUND: Previous studies associate lipid peroxidation with long-term memory (LTM) failure in a gastropod model (Lymnaea stagnalis) of associative learning and memory. This process involves activation of Phospholipase A(2) (PLA(2)), an enzyme mediating the release of fatty acids such as arachidon...

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Detalles Bibliográficos
Autores principales: Hermann, Petra M, Park, Deborah, Beaulieu, Emily, Wildering, Willem C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750374/
https://www.ncbi.nlm.nih.gov/pubmed/23915010
http://dx.doi.org/10.1186/1471-2202-14-83

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750374/
https://www.ncbi.nlm.nih.gov/pubmed/23915010
http://dx.doi.org/10.1186/1471-2202-14-83

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