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Pronounced cancer resistance in a subterranean rodent, the blind mole-rat, Spalax: in vivo and in vitro evidence

BACKGROUND: Subterranean blind mole rats (Spalax) are hypoxia tolerant (down to 3% O(2)), long lived (>20 years) rodents showing no clear signs of aging or aging related disorders. In 50 years of Spalax research, spontaneous tumors have never been recorded among thousands of individuals. Here we...

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Detalles Bibliográficos
Autores principales: Manov, Irena, Hirsh, Mark, Iancu, Theodore C, Malik, Assaf, Sotnichenko, Nick, Band, Mark, Avivi, Aaron, Shams, Imad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750378/
https://www.ncbi.nlm.nih.gov/pubmed/23937926
http://dx.doi.org/10.1186/1741-7007-11-91