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Pronounced cancer resistance in a subterranean rodent, the blind mole-rat, Spalax: in vivo and in vitro evidence
BACKGROUND: Subterranean blind mole rats (Spalax) are hypoxia tolerant (down to 3% O(2)), long lived (>20 years) rodents showing no clear signs of aging or aging related disorders. In 50 years of Spalax research, spontaneous tumors have never been recorded among thousands of individuals. Here we...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750378/ https://www.ncbi.nlm.nih.gov/pubmed/23937926 http://dx.doi.org/10.1186/1741-7007-11-91 |