Cargando…

HIV-1 capsid undergoes coupled binding and isomerization by the nuclear pore protein NUP358

BACKGROUND: Lentiviruses such as HIV-1 can be distinguished from other retroviruses by the cyclophilin A-binding loop in their capsid and their ability to infect non-dividing cells. Infection of non-dividing cells requires transport through the nuclear pore but how this is mediated is unknown. RESUL...

Descripción completa

Detalles Bibliográficos
Autores principales: Bichel, Katsiaryna, Price, Amanda J, Schaller, Torsten, Towers, Greg J, Freund, Stefan MV, James, Leo C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750474/
https://www.ncbi.nlm.nih.gov/pubmed/23902822
http://dx.doi.org/10.1186/1742-4690-10-81