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Dysregulated Tim-3 expression on natural killer cells is associated with increased Galectin-9 levels in HIV-1 infection

BACKGROUND: Natural killer (NK) cells constitutively express high levels of Tim-3, an immunoregulatory molecule recently proposed to be a marker for mature and functional NK cells. Whether HIV-1 infection modulates the expression of Tim-3 on NK cells, or the levels of its ligand Galectin-9 (Gal-9),...

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Detalles Bibliográficos
Autores principales: Jost, Stephanie, Moreno-Nieves, Uriel Y, Garcia-Beltran, Wilfredo F, Rands, Keith, Reardon, Jeff, Toth, Ildiko, Piechocka-Trocha, Alicja, Altfeld, Marcus, Addo, Marylyn M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750478/
https://www.ncbi.nlm.nih.gov/pubmed/23866914
http://dx.doi.org/10.1186/1742-4690-10-74