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Dysregulated Tim-3 expression on natural killer cells is associated with increased Galectin-9 levels in HIV-1 infection
BACKGROUND: Natural killer (NK) cells constitutively express high levels of Tim-3, an immunoregulatory molecule recently proposed to be a marker for mature and functional NK cells. Whether HIV-1 infection modulates the expression of Tim-3 on NK cells, or the levels of its ligand Galectin-9 (Gal-9),...
Autores principales: | Jost, Stephanie, Moreno-Nieves, Uriel Y, Garcia-Beltran, Wilfredo F, Rands, Keith, Reardon, Jeff, Toth, Ildiko, Piechocka-Trocha, Alicja, Altfeld, Marcus, Addo, Marylyn M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750478/ https://www.ncbi.nlm.nih.gov/pubmed/23866914 http://dx.doi.org/10.1186/1742-4690-10-74 |
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