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Quantification of total T-cell receptor diversity by flow cytometry and spectratyping

BACKGROUND: T-cell receptor diversity correlates with immune competency and is of particular interest in patients undergoing immune reconstitution. Spectratyping generates data about T-cell receptor CDR3 length distribution for each BV gene but is technically complex. Flow cytometry can also be used...

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Detalles Bibliográficos
Autores principales: Ciupe, Stanca M, Devlin, Blythe H, Markert, Mary Louise, Kepler, Thomas B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750526/
https://www.ncbi.nlm.nih.gov/pubmed/23914737
http://dx.doi.org/10.1186/1471-2172-14-35