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Quantification of total T-cell receptor diversity by flow cytometry and spectratyping

BACKGROUND: T-cell receptor diversity correlates with immune competency and is of particular interest in patients undergoing immune reconstitution. Spectratyping generates data about T-cell receptor CDR3 length distribution for each BV gene but is technically complex. Flow cytometry can also be used...

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Detalles Bibliográficos
Autores principales:	Ciupe, Stanca M, Devlin, Blythe H, Markert, Mary Louise, Kepler, Thomas B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750526/ https://www.ncbi.nlm.nih.gov/pubmed/23914737 http://dx.doi.org/10.1186/1471-2172-14-35

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