Cargando…

Mitochondria-targeted antioxidant MitoQ ameliorates experimental mouse colitis by suppressing NLRP3 inflammasome-mediated inflammatory cytokines

BACKGROUND: MitoQ is a mitochondria-targeted derivative of the antioxidant ubiquinone, with antioxidant and anti-apoptotic functions. Reactive oxygen species are involved in many inflammatory diseases including inflammatory bowel disease. In this study, we assessed the therapeutic effects of MitoQ i...

Descripción completa

Detalles Bibliográficos
Autores principales: Dashdorj, Amarjargal, KR, Jyothi, Lim, Sangbin, Jo, Ara, Nguyen, Minh Nam, Ha, Joohun, Yoon, Kyung-Sik, Kim, Hyo Jong, Park, Jae-Hoon, Murphy, Michael P, Kim, Sung Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750576/
https://www.ncbi.nlm.nih.gov/pubmed/23915129
http://dx.doi.org/10.1186/1741-7015-11-178