Mitochondria-targeted antioxidant MitoQ ameliorates experimental mouse colitis by suppressing NLRP3 inflammasome-mediated inflammatory cytokines

BACKGROUND: MitoQ is a mitochondria-targeted derivative of the antioxidant ubiquinone, with antioxidant and anti-apoptotic functions. Reactive oxygen species are involved in many inflammatory diseases including inflammatory bowel disease. In this study, we assessed the therapeutic effects of MitoQ i...

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Detalles Bibliográficos
Autores principales: Dashdorj, Amarjargal, KR, Jyothi, Lim, Sangbin, Jo, Ara, Nguyen, Minh Nam, Ha, Joohun, Yoon, Kyung-Sik, Kim, Hyo Jong, Park, Jae-Hoon, Murphy, Michael P, Kim, Sung Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750576/
https://www.ncbi.nlm.nih.gov/pubmed/23915129
http://dx.doi.org/10.1186/1741-7015-11-178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750576/
https://www.ncbi.nlm.nih.gov/pubmed/23915129
http://dx.doi.org/10.1186/1741-7015-11-178

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