Autophagy-mediated turnover of Dynamin-related Protein 1

BACKGROUND: Drp1 is the primary protein responsible for mitochondrial fission. Perturbations of mitochondrial morphology and increased fission are seen in neurodegeneration. While Drp1 degradation induced by Parkin overexpression can be prevented by proteasome inhibition, there are numerous links be...

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Detalles Bibliográficos
Autores principales: Purnell, Phillip R, Fox, Howard S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750610/
https://www.ncbi.nlm.nih.gov/pubmed/23937156
http://dx.doi.org/10.1186/1471-2202-14-86

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750610/
https://www.ncbi.nlm.nih.gov/pubmed/23937156
http://dx.doi.org/10.1186/1471-2202-14-86

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