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Autophagy-mediated turnover of Dynamin-related Protein 1
BACKGROUND: Drp1 is the primary protein responsible for mitochondrial fission. Perturbations of mitochondrial morphology and increased fission are seen in neurodegeneration. While Drp1 degradation induced by Parkin overexpression can be prevented by proteasome inhibition, there are numerous links be...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750610/ https://www.ncbi.nlm.nih.gov/pubmed/23937156 http://dx.doi.org/10.1186/1471-2202-14-86 |