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Immunogenicity, reactogenicity and safety of an inactivated quadrivalent influenza vaccine candidate versus inactivated trivalent influenza vaccine: a phase III, randomized trial in adults aged ≥18 years

BACKGROUND: Two antigenically distinct influenza B lineages have co-circulated since the 1980s, yet inactivated trivalent influenza vaccines (TIVs) include strains of influenza A/H1N1, A/H3N2, and only one influenza B from either the Victoria or Yamagata lineage. This means that exposure to B-lineag...

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Detalles Bibliográficos
Autores principales: Kieninger, Dorothee, Sheldon, Eric, Lin, Wen-Yuan, Yu, Chong-Jen, Bayas, Jose M, Gabor, Julian J, Esen, Meral, Fernandez Roure, Jose Luis, Narejos Perez, Silvia, Alvarez Sanchez, Carmen, Feng, Yang, Claeys, Carine, Peeters, Mathieu, Innis, Bruce L, Jain, Varsha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750613/
https://www.ncbi.nlm.nih.gov/pubmed/23883186
http://dx.doi.org/10.1186/1471-2334-13-343