USP1 deubiquitinase: cellular functions, regulatory mechanisms and emerging potential as target in cancer therapy

Reversible protein ubiquitination is emerging as a key process for maintaining cell homeostasis, and the enzymes that participate in this process, in particular E3 ubiquitin ligases and deubiquitinases (DUBs), are increasingly being regarded as candidates for drug discovery. Human DUBs are a group o...

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Detalles Bibliográficos
Autores principales: García-Santisteban, Iraia, Peters, Godefridus J, Giovannetti, Elisa, Rodríguez, Jose Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750636/
https://www.ncbi.nlm.nih.gov/pubmed/23937906
http://dx.doi.org/10.1186/1476-4598-12-91

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750636/
https://www.ncbi.nlm.nih.gov/pubmed/23937906
http://dx.doi.org/10.1186/1476-4598-12-91

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